Adresse
Université de Rennes 1, Campus de Villejean, 2 Avenue du Pr Léon Bernard - CS 34317
35043 Rennes
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Contact
courriel : vincent.cattoir@univ-rennes.fr
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| Site web :
http://biochpharma.univ-rennes.fr/
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| Taille en ETP (sans compter les stagiaires):
entre 10 et 50.
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Descriptif :
The BRM (Bacterial RNAs & Medicine) mono-team research unit is jointly affiliated to Inserm and University of Rennes with strong links with the Rennes University Hospital (the Department of Clinical Bacteriology, the National Reference Center “Antibiorésistance”, the Department of Infectious Diseases and the Clinical Investigation Center). It is composed of both researchers and clinicians developing a transdisciplinary and translational research at the interface of microbiology, biochemistry, molecular and cell biology, chemistry and clinics. BRM uses ‘state-of-the-art’ complementary approaches from molecular mechanisms to ‘omics’, phenotypes, host-bacteria interactions, as well as different animal models of bacterial infections to unravel mechanisms of bacterial adaptation. The ambition of the team is to understand how bacterial pathogens reprogram gene expression through RNA and protein regulators, to develop novel diagnostic tools and therapeutics against multi-drug resistant (MDR) bacteria including Staphylococcus aureus, Enterococcus faecium and Enterobacter cloacae complex. Three interconnected axes are developed in the team: 1) discovery of physiological and pathogenicity implications of RNA and protein regulators , 2) study of host-pathogen interactions and antibiotic persistence, and 3) Mechanisms of antimicrobial resistance and development of novel antibacterial strategies
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| Année de création :
2008
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| Mission de la structure :
Recherche
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| Mode de gestion de la structure :
Non renseigné.
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| SIRET de la structure :
13003051300019
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Classement scientifique ERC
- LS6 : Immunity, Infection and Immunotherapy : The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
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Domaine scientifique
- 5 : Biologie, médecine et santé 2008 0
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Ecole(s) doctorale(s) de rattachement
-
ED 637 - SCIENCES DE LA VIE ET DE LA SANTÉ (SVS), depuis le 01/09/2022, fin d'accréditation le 31/12/2027
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Rattachée au(x) programme(s) LOLF suivant(s):
- prg150-06 : Recherche universitaire en sciences de la vie, biotechnologies et santé
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Rattachée au(x) thème(s) de recherche suivant(s):
Microbiologie et Biologie moléculaire;
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Origine de la structure
intégration en 2008 de :
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200015970N - ETUDE STRUCTURALE ET CONCEPTION DE NOUVEAUX ANTIBIOTIQUES SE FIXANT À L'ARNTM
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Liens avec d'autres structures :
Aucun.
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Site ESR :
Aucun.
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